KEGG: new perspectives on genomes, pathways, diseases and drugs
نویسندگان
چکیده
منابع مشابه
KEGG: new perspectives on genomes, pathways, diseases and drugs
KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an encyclopedia of genes and genomes. Assigning functional meanings to genes and genomes both at the molecular and higher levels is the primary objective of the KEGG database project. Molecular-level functions are stored in the KO (KEGG Orthology) database, where each KO is defined as a functional ortholog of genes and proteins. Higher...
متن کاملKEGG: Kyoto Encyclopedia of Genes and Genomes
Kyoto Encyclopedia of Genes and Genomes (KEGG) is a knowledge base for systematic analysis of gene functions in terms of the networks of genes and molecules. The major component of KEGG is the PATHWAY database that consists of graphical diagrams of biochemical pathways including most of the known metabolic pathways and some of the known regulatory pathways. The pathway information is also repre...
متن کاملKEGG for representation and analysis of molecular networks involving diseases and drugs
Most human diseases are complex multi-factorial diseases resulting from the combination of various genetic and environmental factors. In the KEGG database resource (http://www.genome.jp/kegg/), diseases are viewed as perturbed states of the molecular system, and drugs as perturbants to the molecular system. Disease information is computerized in two forms: pathway maps and gene/molecule lists. ...
متن کاملThe Kyoto Encyclopedia of Genes and Genomes—KEGG
is organized into three sections: pathway information , genomic information, and computational tools. The pathway information section includes searchable pathway maps and orthologue tables of metabolic and regulatory pathways. There are also extensive catalogues of diseases (human), organisms (completely sequenced genomes or chromosomes), cells (cell lineages), enzymes and`compounds'. All of th...
متن کاملKEGG for linking genomes to life and the environment
KEGG (http://www.genome.jp/kegg/) is a database of biological systems that integrates genomic, chemical and systemic functional information. KEGG provides a reference knowledge base for linking genomes to life through the process of PATHWAY mapping, which is to map, for example, a genomic or transcriptomic content of genes to KEGG reference pathways to infer systemic behaviors of the cell or th...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2016
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkw1092